Of course I'm serious. Crumb is a genius. He would most likely create an irreverent deck that would skewer some sacred cows. I think he could create a very thoughtful deck. Crumb goes way beyond vulgarity.
Yeah, Crumb was by no means just some cheap panderer. He is a divisive artist in today's PC world, but his universe of burlesque urbania cluttered with endless detail would be perfectly suited to the tarot medium and popped into my mind while reading this thread.
I'd be a fan of Gregory Crewdson, Edward Hopper, Alexander McQueen costumery, Saul Bass, Erte, Beardsley, Tenniel, Maxfield Parrish, and a dozen others echoed in the previous pages.