I have Saturn in Pisces (along with Sun and Mercury) at 29° 56' - so the very last minutes of Pisces - in the 11th House (where my Sun and Mercury are also situated, as well as my Aries Venus). My Beloved has Saturn in Scorpio in the 6th House.
I don't know about it being any more karmic or fated than in other signs. It's certainly not at home in feminine, water signs like Pisces or Scorpio. Mine has little essential dignity, though it is in its term. My Beloved's is peregrine, and stuck in the house of illness. He became a doctor
.
I described my Saturn elsewhere as a querulous and somewhat ineffective old man, though he is great at making me feel guilty about all my shortcomings and giving me occasional self-pity-fests. He is also a bit of a loner, which makes everyone else in that 11th house lonely. The trouble is - when it comes to disciplining myself, he's not that useful. I tend to rely more on my strong Scorpio Mars (who is in a sign he rules and in his house of joy) to whip myself into action.
I don't know if it's linked to its position in the 11th house or to its sign, or both, but I have spent much of my life working to better the lot of others - as a humanitarian for several years and now retraining as a natural therapist; and much of my writing is concerned with other people (i.e. I am not consciously interested in autobiographical works, in either fiction or non-fiction).
My Beloved is more likely to buckle down under the impulse of his strict, somewhat joyless Scorpio Saturn, though he too relies on a strong energetic Mars a fair amount (in Aries and in the 10th house).