Interesting question, I'm looking forward to reading the other responses you will get.
My take is very simple: I don't make a specific spread out of it, but deal clarification cards to the original spread. That is I ask a question like "What does this mean?" (often I get a "direction" from the card there from the start, and ask for some depth to understand better)
This means I don't do a specific spread, but take a more "flexible" approach - do I need to know something, I'll just ask for THAT and nothing else...!
Hope you'll get lot's of othe replies, I'll read them with a huge interest!