Have you moved recently? I had this problem when I moved. Try to cleanse the space a bit, if you can. And let the cards get used to the new place, too.
Are you emotionally tired or stessed? I find that if I am tired or stressed - just the the time I need my Tarot - it is most unlcear to me. Paradox! If that is the case, I'd suggest you: 1) Try a different spread; 2) Relax and focus your mind on your question.
And finally, sometimes I find that I *think* I am asking about one area of my life and it seems another area of my life is "interrupting" and this can seem to confuse the interpretation. I've seen this with people I've read for, too. If you think this might be happening to you, you could try to just "read" the cards straight - try to place no query on them - and see if they perhaps make more sense about another aspect of your life that you didn't realize was coming
through.
If none of the above are applicable or work, I'd take a rest for a week or two, as Liliana suggests. And don't try to do multiple self readings in one day!