Great topic! While writing a study guide for new students, I went on a fascinating journey through the literature (or at least that fragment of it that sits on my bookshelf), to render the node definitions down into their essence as viewed by both traditional writers and modern psychological/esoteric interpreters. I'm sure there is more out there (I'm missing Schulman's Volume I, for example) but what I did find was illuminating. I copied-and-pasted my results below.
My North Node is in Taurus, my South Node is in Scorpio.
My MNN is in the 6th House, my MSN is in the 12th House (Placidus).
The only close aspects are MNN square 9th House Pluto within 4 minutes of arc and parallel 9th House Saturn within 22 minutes of arc. Pluto and Saturn are also near-conjunct in Leo within 6 degrees.
Rob Hand once said at a lecture I attended "The Moon's nodes mean "connections, period!" I think this was the opinion of the German astrologers in the last half of the 20th century, when this comment was made. I'm not sure what Rob thinks of it today.
Below is what I gleaned from my search of the literature:
Moon's North Node – Considered a benefic influence by traditional astrologers
Traditional Meanings: Increase and abundance in the matters related to its house placement (through no conscious effort on the part of the native);
Modern Functional Meanings: The forming of associations, connections and relationships, the life's destiny or calling, point of greatest attunement to universal ideals and values; prevailing social trends that represent opportunities
Modern Psychological Meanings: Spiritual power and integration, directed action, where one has work to do;
Modern Esoteric Meanings: Where one applies the lessons carried over from past lives, also the lessons to be learned in this lifetime
Moon's South Node - Considered a malefic influence by traditional astrologers
Traditional Meanings: Decrease and loss in the matters related to its house placement (while still demanding effort and sacrifice with no promise of reward);
Modern Functional Meanings: The dissolving of associations, connections and relationships, the influence of past habits on present attitudes and behaviors; point of greatest vulnerability to unconscious domination by collective priorities
Modern Psychological Meanings: The line of least resistance, one's “comfort zone” where one is most at home and doesn't need to put forth any effort; spontaneous action, emotional power, the point of release for toxic content;
Modern Esoteric Meanings: The lessons and experiences carried over from past lives into the present life, also past experiences that need no further emphasis and that can be left behind in the current lifetime; karmic influences of one's past conduct; fateful occurrences
My social (as opposed to professional) connections with other people (other than my wife of 34 years and one of my eight siblings) have always been somewhat tenuous at best. I'm always looking for deep philosophical and intellectual links and generally finding only shallow social intercourse. Consequently I don't have many close friends, nor do I really miss them. I tend to be very serious-minded, although with a wry (some say slightly twisted) sense of humor. I was quite fortunate in work; my series of bosses over the years highly valued and respected my productive and pragmatic mental focus, which I was able to parlay into an early and comfortable retirement. I made some strong connections in the workplace that stayed with me throughout a 31-year technological career at the same company (in, I might add, a very Plutonian industry). I came equipped with good intellectual equipment (I've been a member of Mensa off and on over the years), but I'm having to learn to be more emotionally open and less distrustful, since I almost always suspect a hidden self-serving agenda behind every human action. I see these traits as earmarks of the cadent, fixed T-square and the 6th-12th house polarity, along with the 9th-house Pluto-Saturn emphasis.
As the Wizard of Oz might have told Dorothy in an alternate universe: "Oh no, my dear, I'm a very good man, I'm just a very bad schmoozer."